Article
Association of relative leukocyte telomere length and genetic variants in telomere-related genes (TERT, TERT-CLPTM1, TRF1, TNKS2, TRF2) with atrophic age-related macular degeneration.
Ophthalmic genetics - 1 Apr 2021
Banevicius Mantas, Gedvilaite Greta, Vilkeviciute Alvita, Kriauciuniene Loresa, Zemaitiene Reda, Liutkeviciene Rasa
Abstract excerpt
Background: In an experimental model, telomere shortening inhibits neovascularization. It is thus possible that telomere shortening might have a role in the pathogenesis of geographic atrophy in case of age-related macular degeneration (AMD). This is why we aimed to find any associated differences of telomere length and genetic variants in telomere-related genes (TERT, TERT-CLPTM1, TRF1, TNKS2, and TRF2) in...
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