Article
Aberrant leukocyte telomere length in Birdshot Uveitis.
PloS one - 1 Jan 2017
Vazirpanah Nadia, Verhagen Fleurieke H, Rothova Anna, Missotten Tom O A R, van Velthoven Mirjam, Den Hollander Anneke I, Hoyng Carel B, Radstake Timothy R D J, Broen Jasper C A, Kuiper Jonas J W
Abstract excerpt
PURPOSE: Birdshot Uveitis (BU) is an archetypical chronic inflammatory eye disease, with poor visual prognosis, that provides an excellent model for studying chronic inflammation. BU typically affects patients in the fifth decade of life. This suggests that it may represent an age-related chronic inflammatory disease, which has been linked to increased erosion of telomere length of leukocytes. METHODS: To study...
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