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Article

Targeting Cancer Stem Cells with Repurposed Drugs to Improve Current Therapies.

Recent patents on anti-cancer drug discovery - 1 Jan 2021

Fong Dunne, Christensen Chase T, Chan Marion M

Abstract excerpt

BACKGROUND: Cancer is a multistep process involving genetic and epigenetic changes in the somatic genome. Genetic mutations as well as environmental factors lead to the initiation, promotion, and progression of cancer. Metastasis allows cancer cells to spread via circulatory and lymphatic systems; secondary tumorigenesis typically leads to a fatal outcome. Recent experimental evidence suggests that Cancer Stem...

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PMID: 33563159
DOI: 10.2174/1574892816666210208232251

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