Sinoatrial node pacemaker cells: cardiomyocyte- or neuron-like cells?

Abstract excerpt

nature of SANPCs remains incompletely known.In general, SANPCs have long been considered as specialized cardiomyocytes (Van Eif et al., 2018;Linscheid et al., 2019;Galang et al., 2020; ).However, SANPCs do not have myofibril and T-tube, thus not sharing the contractility property of cardiomyocytes (Satoh, 2003;Protze et al., 2017).Interestingly, SANPCs share some electrophysiological characteristics with neurons:...

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