Article
Air Trapping Is Associated with Heterozygosity for Alpha-1 Antitrypsin Mutations in Patients with Asthma.
Respiration; international review of thoracic diseases - 1 Jan 2000
Aiello Marina, Ghirardini Marianna, Marchi Laura, Frizzelli Annalisa, Pisi Roberta, Ferrarotti Ilaria, Bertorelli Giuseppina, Chetta Alfredo
Abstract excerpt
BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is a hereditary disorder involving lungs, characterized by low serum concentration of the protein alpha-1 antitrypsin (AAT) also called proteinase inhibitor (PI). Asthma is common in AATD patients, but there are only few data on respiratory function in asthmatic patients with AATD. OBJECTIVES: The aim of the study was to evaluate lung function in asthmatic...
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