Article
Alpha-1 deficiency in severe asthma patients.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 May 2024
Zappa M, Grossi S, Pignatti P, Pini L, Centis R, Migliori G B, Ardesi F, Sotgiu G, Corsico A G, Spanevello A, Visca D
Abstract excerpt
<sec id="st1"><title>INTRODUCTION</title>Alpha-1 antitrypsin (AAT) deficiency, an autosomal co-dominant condition, decreases protein concentration and activity at both serum and tissue levels. Few studies investigated whether the type of SERPINA1 gene phenotype in patients with severe asthma can influence symptoms and disease control during follow-up.</sec><sec id="st2"><title>OBJECTIVE</title>To assess whether...
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