Development of a Genetic Risk Score to predict the risk of overweight and obesity in European adolescents from the HELENA study.

doi:10.1038/s41598-021-82712-4

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Article

Development of a Genetic Risk Score to predict the risk of overweight and obesity in European adolescents from the HELENA study.

Scientific reports - 4 Feb 2021

Seral-Cortes Miguel, Sabroso-Lasa Sergio, De Miguel-Etayo Pilar, Gonzalez-Gross Marcela, Gesteiro Eva, Molina-Hidalgo Cristina, De Henauw Stefaan, Gottrand Frederic, Mavrogianni Christina, Manios Yannis, Plada Maria, Widhalm Kurt, Kafatos Anthony, Erhardt Éva, Meirhaeghe Aline, Salazar-Tortosa Diego, Ruiz Jonatan, Moreno Luis A, Esteban Luis Mariano, Labayen Idoia

Abstract excerpt

Obesity is the result of interactions between genes and environmental factors. Since monogenic etiology is only known in some obesity-related genes, a genetic risk score (GRS) could be useful to determine the genetic predisposition to obesity. Therefore, the aim of our study was to build a GRS able to predict genetic predisposition to overweight and obesity in European adolescents. A total of 1069 adolescents...

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PMID: 33542408
DOI: 10.1038/s41598-021-82712-4
PMCID: PMC7862459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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