Interaction Effect of the Mediterranean Diet and an Obesity Genetic Risk Score on Adiposity and Metabolic Syndrome in Adolescents: The HELENA Study.

doi:10.3390/nu12123841

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Article

Interaction Effect of the Mediterranean Diet and an Obesity Genetic Risk Score on Adiposity and Metabolic Syndrome in Adolescents: The HELENA Study.

Nutrients - 16 Dec 2020

Seral-Cortes Miguel, Sabroso-Lasa Sergio, De Miguel-Etayo Pilar, Gonzalez-Gross Marcela, Gesteiro Eva, Molina-Hidalgo Cristina, De Henauw Stefaan, Erhardt Éva, Censi Laura, Manios Yannis, Karaglani Eva, Widhalm Kurt, Kafatos Anthony, Beghin Laurent, Meirhaeghe Aline, Salazar-Tortosa Diego, Ruiz Jonatan R, Moreno Luis A, Esteban Luis Mariano, Labayen Idoia

Abstract excerpt

Obesity and metabolic syndrome (MetS) are worldwide major health challenges. The Mediterranean diet (MD) is associated with a better cardiometabolic profile, but these beneficial effects may be influenced by genetic variations, modulating the predisposition to obesity or MetS. The aim was to assess whether interaction effects occur between an obesity genetic risk score (obesity-GRS) and the MD on adiposity and...

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PMID: 33339255
DOI: 10.3390/nu12123841
PMCID: PMC7766705

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