Article
[Genetic background in common forms of obesity - from studies on identical twins to candidate genes of obesity].
Casopis lekaru ceskych - 1 Jan 2014
Bendlová Běla, Lukášová Petra, Vaňková Markéta, Vejražková Daniela, Bradnová Olga, Včelák Josef, Stanická Soňa, Zamrazilová Hana, Aldhoon-Hainerová Irena, Dušátková Lenka, Kunešová Marie, Hainer Vojtěch
Abstract excerpt
Common obesity is a result of interaction between genes and environmental/lifestyle factors, with heritability estimates 40-70%. Not only the susceptibility to obesity but also the success of weight management depends on the genetic background of each individual. This paper summarizes the up-to-date knowledge on genetic causes of common obesities. Introduction of genome-wide association studies (GWAS) led to an...
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