Article
The body mass index increases the genetic risk scores' ability to predict risk of hepatic damage in European adolescents: The HELENA study.
European journal of clinical investigation - 1 Dec 2023
Seral-Cortes Miguel, Sabroso-Lasa Sergio, Gonzalez-Gross Marcela, Quesada-Gonzalez Carlos, Stehle Peter, Gottrand Frederic, Marcos Ascension, Esperanza-Diaz Ligia, Manios Yannis, Androutsos Odysseas, Widhalm Kurt, Molnar Denes, Huybrechts Inge, Muntaner Manon, Meirhaeghe Aline, Salazar-Tortosa Diego, Ruiz Jonatan R, Esteban Luis Mariano, Labayen Idoia, Moreno Luis A
Abstract excerpt
BACKGROUND: Hepatic disorders are often complex and multifactorial, modulated by genetic and environmental determinants. During the last years, the hepatic disease has been progressively established from early stages in life. The use of genetic risk scores (GRS) to predict the genetic susceptibility to a particular phenotype among youth has gained interest in recent years. Moreover, the alanine aminotransferase...
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