Article
Dynamics of chromosomal target search by a membrane-integrated one-component receptor.
PLoS computational biology - 1 Feb 2021
Martini Linda, Brameyer Sophie, Hoyer Elisabeth, Jung Kirsten, Gerland Ulrich
Abstract excerpt
Membrane proteins account for about one third of the cellular proteome, but it is still unclear how dynamic they are and how they establish functional contacts with cytoplasmic interaction partners. Here, we consider a membrane-integrated one-component receptor that also acts as a transcriptional activator, and analyze how it kinetically locates its specific binding site on the genome. We focus on the case of...
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