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Article

Diet‐induced DNA methylation within the hypothalamic arcuate nucleus and dysregulated leptin and insulin signaling in the pathophysiology of obesity

5 Sept 2019

Abstract excerpt

Obesity rates continue to rise in an unprecedented manner in what could be the most rapid population-scale shift in human phenotype ever to occur. Increased consumption of unhealthy, calorie-dense foods, coupled with sedentary lifestyles, is the main factor contributing to a positive energy balance and the development of obesity. Leptin and insulin are key hormones implicated in pathogenesis of this disorder and...

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Share to Dietary Effects on Health
Share to Epigenetics and DNA Methylation
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PMID: 31660128
DOI: 10.1002/fsn3.1169

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