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Article

Weight Loss after Gastric Bypass Surgery in Human Obesity Remodels Promoter Methylation

1 Apr 2013

Abstract excerpt

DNA methylation provides a mechanism by which environmental factors can control insulin sensitivity in obesity. Here, we assessed DNA methylation in skeletal muscle from obese people before and after Roux-en-Y gastric bypass (RYGB). Obesity was associated with altered expression of a subset of genes enriched in metabolic process and mitochondrial function. After weight loss, the expression of the majority of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23583180
DOI: 10.1016/j.celrep.2013.03.018

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