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Article

Clinical epigenetics and restoring of metabolic health in severely obese patients undergoing batriatric and metabolic surgery

2 Oct 2021

Abstract excerpt

Epigenetic-sensitive mechanisms, mainly DNA methylation, mirror the relationship between environmental and genetic risk factors able to affect the sensitiveness to development of obesity and its comorbidities. Bariatric and metabolic surgery may reduce obesity-related cardiovascular risk through tissue-specific DNA methylation changes. Among the most robust results, differential promoter methylation of ACACA,...

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PMID: 34599748
DOI: 10.1007/s13304-021-01162-9

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