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Article

Effect of inosine monophosphate dehydrogenase-1 gene polymorphisms on mycophenolate mofetil effectiveness in neuromyelitis optica spectrum disorder patients.

Multiple sclerosis and related disorders - 1 Apr 2021

Liu Lanzhi, Luo Zhaohui, Liu Fan, Shang Danqing, Qiu Dongxu, Jiao Xiao, Zhou Xiaoliang, Chen Si, Wu Junfang, Li Jing

Abstract excerpt

BACKGROUND: Inosine monophosphate dehydrogenase-1 is the target of mycophenolate mofetil. This research investigated the association between the gene polymorphism of inosine monophosphate dehydrogenase-1 and effectiveness of mycophenolate mofetil therapy in neuromyelitis optica spectrum disorder patients. METHODS: Fifty-nine neuromyelitis optica spectrum disorder patients accepted Mycophenolate Mofetil therapy...

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PMID: 33524926
DOI: 10.1016/j.msard.2021.102779

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