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Are IVS4 SNPs of OLR1 gene associated with coronary artery disease: Is there a linkage between IVS4 SNPs?

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Mar 2018

Kurnaz-Gomleksiz Ozlem, Kucukhuseyin Ozlem, Ozkok Elif, Bugra Zehra, Ozturk Oguz, Yilmaz-Aydogan Hulya

Abstract excerpt

BACKGROUND: The OLR1 gene has been identified as a candidate gene for coronary artery disease (CAD). Six single-nucleotide polymorphisms (SNPs) of the OLR1 gene located within intron 4 (IVS4-27G>C, IVS4-73C>T, IVS4-14A>G), intron 5 (IVS5-70A>G, IVS5-27G>T) and 3'UTR (188C>T) comprise a linkage disequilibrium (LD) block, which is strongly associated with the elevated risk of CAD. OBJECTIVES: We aimed to...

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Identifiers

PMID: 29558038
DOI: 10.17219/acem/68395

Genes

OLR1
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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