Article
Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients.
Anticancer research - 1 Feb 2021
Papadaki Maria A, Aggouraki Despoina, Vetsika Eleni-Kyriaki, Xenidis Nikolaos, Kallergi Galaktea, Kotsakis Athanasios, Georgoulias Vassilis
Abstract excerpt
BACKGROUND: To investigate the correlation between circulating tumor cells (CTCs) bearing cancer stem cell (CSC) and epithelial-to-mesenchymal (EMT) phenotypes and the different immunosuppressive cells in peripheral blood of patients with metastatic breast cancer (mBC). MATERIALS AND METHODS: Blood was obtained from 38 pre-treated patients with mBC before a new line of treatment. CTC detection and...
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