Association between ABO haplotypes and the risk of venous thrombosis: impact on disease risk estimation.

doi:10.1182/blood.2020008997

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Article

Association between ABO haplotypes and the risk of venous thrombosis: impact on disease risk estimation.

Blood - 29 Apr 2021

Goumidi Louisa, Thibord Florian, Wiggins Kerri L, Li-Gao Ruifang, Brown Mickael R, van Hylckama Vlieg Astrid, Souto Joan-Carles, Soria José-Manuel, Ibrahim-Kosta Manal, Saut Noémie, Daian Delphine, Olaso Robert, Amouyel Philippe, Debette Stéphanie, Boland Anne, Bailly Pascal, Morrison Alanna C, Mook-Kanamori Denis O, Deleuze Jean-François, Johnson Andrew, de Vries Paul S, Sabater-Lleal Maria, Chiaroni Jacques, Smith Nicholas L, Rosendaal Frits R, Chasman Daniel I, Trégouët David-Alexandre, Morange Pierre-Emmanuel

Abstract excerpt

Genetic risk score (GRS) analysis is a popular approach to derive individual risk prediction models for complex diseases. In venous thrombosis (VT), such type of analysis shall integrate information at the ABO blood group locus, which is one of the major susceptibility loci. However, there is no consensus about which single nucleotide polymorphisms (SNPs) must be investigated when properly assessing association...

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Identifiers

PMID: 33512453
DOI: 10.1182/blood.2020008997
PMCID: PMC8085481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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