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Article

Characterization of New ATM Deletion Associated with Hereditary Breast Cancer.

Genes - 21 Jan 2021

Parenti Sandra, Rabacchi Claudio, Marino Marco, Tenedini Elena, Artuso Lucia, Castellano Sara, Carretta Chiara, Mallia Selene, Cortesi Laura, Toss Angela, Barbieri Elena, Manfredini Rossella, Luppi Mario, Trenti Tommaso, Tagliafico Enrico

Abstract excerpt

Next-generation sequencing (NGS)-based cancer risk screening with multigene panels has become the most successful method for programming cancer prevention strategies. ATM germ-line heterozygosity has been described to increase tumor susceptibility. In particular, families carrying heterozygous germ-line variants of ATM gene have a 5- to 9-fold risk of developing breast cancer. Recent studies identified ATM as the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33494414
DOI: 10.3390/genes12020136
PMCID: PMC7911716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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