Article

Characterization of New ATM Deletion Associated with Hereditary Breast Cancer

2020-12-22

Abstract excerpt

Next Generation Sequencing based cancer risk screening with multigene panels has become the most successful method for programming cancer prevention strategies. ATM germ-line heterozygosity has been described as able to increase tumor susceptibility. In particular, families that carry heterozygous germ-line variants of ATM gene show a 5- to 9-fold risk of developing breast cancer. Recent studies identified ATM as...

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Literature Corpus work: 8508411e-11b1-5c83-b5c0-60fd871d1797
DOI: 10.20944/preprints202012.0548.v1

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