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Article

Metabolic Effects of Recurrent Genetic Aberrations in Multiple Myeloma

21 Jan 2021

Abstract excerpt

Oncogene activation and malignant transformation exerts energetic, biosynthetic and redox demands on cancer cells due to increased proliferation, cell growth and tumor microenvironment adaptation. As such, altered metabolism is a hallmark of cancer, which is characterized by the reprogramming of multiple metabolic pathways. Multiple myeloma (MM) is a genetically heterogeneous disease that arises from terminally...

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PMID: 33494394
DOI: 10.3390/cancers13030396

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