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Article

Functional Characterization of Ly49+CD8 T-Cells in Both Normal Condition and During Anti-Viral Response.

Frontiers in immunology - 1 Jan 2020

Shytikov Dmytro, Rohila Deepak, Li Dan, Wang Pengfei, Jiang Mei, Zhang Mingxu, Xu Qin, Lu Linrong

Abstract excerpt

The role of Ly49+CD8 T-cells in the immune system is not clear. Previously, several papers suggested Ly49+CD8 T-cells as immunosuppressors, while multiple studies also suggested their role as potent participants of the immune response. The mechanism of Ly49 expression on CD8 T-cells is also not clear. We investigated phenotype, functions, and regulation of Ly49 expression on murine CD8 T-cells in both normal...

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Chlorocebus aethiops
Host-Pathogen Interactions
Adoptive Transfer
CD8-Positive T-Lymphocytes
Immunologic Memory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Activation

Lymphocytic choriomeningitis virus

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Identifiers

PMID: 33488602
DOI: 10.3389/fimmu.2020.602783
PMCID: PMC7817614

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