Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Factors as Evolvable Biosensors.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 10 May 2021

Umeno Daisuke, Kimura Yuki, Kawai-Noma Shigeko

Abstract excerpt

One of the most prominent features of genetically encoded biosensors (GEBs) is their evolvability-the ability to invent new sensory functions using mutations. Among the GEBs, the transcription factor-based biosensors (TF-biosensors) is the focus of this review. We also discuss how this class of sensors can be highly evolvable and how we can exploit it. With an established platform for directed evolution,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosensing Techniques
Share to Mutation
Share to Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33487602
DOI: 10.2116/analsci.20SCR12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Factors as Evolvable Biosensors.PMID 33487602Read ↗

Evolution-guided engineering of small-molecule biosensorsSemantic proximity Read ↗

Random sequences rapidly evolve into de novo promoters.Semantic proximity Read ↗

Using Latent Chemical Recognition in an Evolved Periplasmic Binding Protein Family to Diversify BiosensorsSemantic proximity Read ↗

Robustness and evolvability: Revisited, redefined and applied.Semantic proximity Read ↗

Development of transcriptional factor-based whole-cell biosensors to monitor and degrade antibiotics using mutant cells obtained via adaptive laboratory evolution.Semantic proximity Read ↗

GroovDB: A database of ligand-inducible transcription factorsSemantic proximity Read ↗

Directed Evolution of the Stringency of the LuxR Vibrio fischeri Quorum Sensor without OFF-State Selection.Semantic proximity Read ↗

Need for speed - finding productive mutations using transcription factor-based biosensors, fluorescence-activated cell sorting and recombineering.Semantic proximity Read ↗

A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensorsSemantic proximity Read ↗

Adaptively responsive hypermutation and its configurational-based regulation due to global position effect.Semantic proximity Read ↗

Using Nature's "Tricks" To Rationally Tune the Binding Properties of Biomolecular Receptors.Semantic proximity Read ↗

Evolverator: An engineered yeast system to drive rapid continuous <i>in vivo</i> evolution of proteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.