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Article

Regulatory effect and mechanism of APN gene on porcine epidemic diarrhea virus resistance.

Gene - 5 Apr 2021

Wang Shiqin, Xu Chao, Shi Jing, Wang Haifei, Wu Shenglong, Bao Wenbin

Abstract excerpt

PURPOSE: The expression level of aminopeptidase N (APN) is evidently correlated with porcine epidemic diarrhea virus (PEDV) infectivity. This study aims to examine the mechanisms regulating APN expression level in response to PEDV infection. METHODS: Quantitative real time PCR was performed herein to detect gene expression dynamics at various timepoints after PEDV infection. Subsequently, CRISPR/Cas9 gene editing...

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Identifiers

PMID: 33482281
DOI: 10.1016/j.gene.2021.145448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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