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Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3

6 Oct 2023

Abstract excerpt

Coronaviruses (CoVs) are a family of the largest RNA viruses that typically cause respiratory, enteric, and hepatic diseases in animals and humans, imposing great threats to the public safety and animal health. Porcine deltacoronavirus (PDCoV), a newly emerging enteropathogenic coronavirus, causes severe diarrhea in suckling piglets all over the world and poses potential risks of cross-species transmission. Here,...

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PMID: 37801439
DOI: 10.1371/journal.ppat.1011702

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