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Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster

18 Jan 2021

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disease characterized by the progressive degeneration of upper and lower motoneurons. Most ALS cases are sporadic but approximately 10% of ALS cases are due to inherited mutations in identified genes. ALS-causing mutations were identified in over 30 genes with superoxide dismutase-1 (SOD1), chromosome 9 open reading frame 72...

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PMID: 33477509
DOI: 10.3390/ijms22020904

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