Article
Whole-exome sequencing of endometriosis identifies frequent alterations in genes involved in cell adhesion and chromatin-remodeling complexes.
Human molecular genetics - 15 Nov 2014
Li Xiaolei, Zhang Yan, Zhao Luyang, Wang Lingxiong, Wu Zhiqiang, Mei Qian, Nie Jing, Li Xiang, Li Yali, Fu Xiaobing, Wang Xiaoning, Meng Yuanguang, Han Weidong
Abstract excerpt
Endometriosis is a complex and enigmatic disease that arises from the interplay among multiple genetic and environmental factors. The defining feature of endometriosis is the deposition and growth of endometrial tissues at sites outside of the uterine cavity. Studies to date have established that endometriosis is heritable but have not addressed the causal genetic variants for this disease. Here, we conducted...
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