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MSIsensor-ct: microsatellite instability detection using cfDNA sequencing data

10 Dec 2020

Abstract excerpt

MOTIVATION: Microsatellite instability (MSI) is a promising biomarker for cancer prognosis and chemosensitivity. Techniques are rapidly evolving for the detection of MSI from tumor-normal paired or tumor-only sequencing data. However, tumor tissues are often insufficient, unavailable, or otherwise difficult to procure. Increasing clinical evidence indicates the enormous potential of plasma circulating cell-free...

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PMID: 33461213
DOI: 10.1093/bib/bbaa402

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