Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic relevance of SMC family gene expression in human sarcoma

30 Dec 2020

Abstract excerpt

OBJECTIVE: To explore the prognostic value of the expression of genes encoding structural maintenance of chromosomes (SMCs) in human sarcoma. RESULTS: We found that the levels of SMC1A, SMC2, SMC3, SMC4, SMC5 and SMC6 mRNA were all higher in most tumors compared to normal tissues, and especially in sarcoma. According to the Cancer Cell Line Encyclopedia (CCLE), SMC1A, SMC2, SMC3, SMC4, SMC5 and SMC6 are also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to Genomic variations and chromosomal abnormalities
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33460400
DOI: 10.18632/aging.202455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic relevance of SMC family gene expression in human sarcomaPMID 33460400Read ↗

Expression Profile and Prognostic Values of SMC Family Members in HCCSemantic proximity Read ↗

Clinical Significance and Integrative Analysis of the SMC Family in Hepatocellular CarcinomaSemantic proximity Read ↗

SMC4, a novel tumor prognostic marker and potential tumor therapeutic targetSemantic proximity Read ↗

Clinical Significance and Bioinformatics Analysis of SMC Family in Pancreatic AdenocarcinomaSemantic proximity Read ↗

Prognosis and Immune Infiltration of Chromobox Family Genes in SarcomaSemantic proximity Read ↗

Expression and Prognostic Value of MCM Family Genes in OsteosarcomaSemantic proximity Read ↗

Integrative Proteogenomic Analyses Identify TOPs as Prognostic Markers and Therapeutic Targets in SarcomaSemantic proximity Read ↗

SMC6 expression & outcome of breast cancer.Semantic proximity Read ↗

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cellsSemantic proximity Read ↗

Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancerSemantic proximity Read ↗

Overexpression of SMC4 predicts a poor prognosis in cervical cancer and facilitates cancer cell malignancy phenotype by activating NF-κB pathway.Semantic proximity Read ↗

GINS1/2/3/4 Upregulation Predicts Poor Prognosis in Human SarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.