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Article

SMC4, a novel tumor prognostic marker and potential tumor therapeutic target

17 Mar 2023

Abstract excerpt

The structural maintenance of chromosome 4 (SMC4) is a member of the ATPase family of chromosomes. The most widely reported function of SMC4, as well as the remaining subunits of whole condensin complexes, is compression and dissociation of sister chromatids, DNA damage repair, DNA recombination, and pervasive transcription of the genome. Studies have also shown that SMC4 plays an exceedingly essential role in...

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PMID: 37007153
DOI: 10.3389/fonc.2023.1117642

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