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Expression and Prognostic Value of MCM Family Genes in Osteosarcoma

22 Jun 2021

Abstract excerpt

We performed a detailed cancer VS normal analysis to explore the expression and prognostic value of minichromosome maintenance (MCM) proteinsin human sarcoma. The mRNA expression levels of the MCM family genes in sarcoma were analyzed using data from ONCOMINE, GEPIA and CCLE databases. KEGG database was used to analyze the function of MCM2-7 complex in DNA replication and cell cycle. QRT-PCR and western blot were...

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PMID: 34239894
DOI: 10.3389/fmolb.2021.668402

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