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Article

Topical Application of Mesenchymal Stem Cell Exosomes Alleviates the Imiquimod Induced Psoriasis-Like Inflammation.

International journal of molecular sciences - 13 Jan 2021

Zhang Bin, Lai Ruenn Chai, Sim Wei Kian, Choo Andre Boon Hwa, Lane Ellen Birgit, Lim Sai Kiang

Abstract excerpt

Severe psoriasis, a chronic inflammatory skin disease is increasingly being effectively managed by targeted immunotherapy but long-term immunotherapy poses health risk and loss of response. Therefore, there is a need for alternative therapy strategies. Mesenchymal stem/stromal cell (MSC) exosomes are widely known for their potent immunomodulatory properties. Here we investigated if topically applied MSC exosomes...

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Identifiers

PMID: 33450859
DOI: 10.3390/ijms22020720
PMCID: PMC7828312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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