Article
Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.
Frontiers in immunology - 1 Jan 2018
Zöller Margot, Zhao Kun, Kutlu Natalia, Bauer Nathalie, Provaznik Jan, Hackert Thilo, Schnölzer Martina
Abstract excerpt
The treatment of autoimmune diseases still poses a major challenge, frequently relying on non-specific immunosuppressive drugs. Current efforts aim at reestablishing self tolerance using immune cells with suppressive activity like the regulatory T cells (Treg) or the myeloid-derived suppressor cells (MDSC). We have demonstrated therapeutic efficacy of MDSC in mouse Alopecia Areata (AA). In the same AA model, we...
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