Immunomodulatory properties of umbilical cord blood-derived small extracellular vesicles and their therapeutic potential for inflammatory skin disorders

Abstract excerpt

<h4>ABSTRACT</h4> Umbilical cord blood (UCB) has long been seen as a rich source of naïve cells with strong regenerative potential, likely mediated by small extracellular vesicles (sEV). More recently, small extracellular vesicles (sEV), such as exosomes, have been shown to play essential roles in cell-to-cell communication, via the transport of numerous molecules, including small RNAs. Often explored for their p...

Topics

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• CD8-Positive T-Lymphocytes
• Cell- and Tissue-Based Therapy
• Coculture Techniques
• Exosomes
• Extracellular vesicles in disease
• Fetal Blood
• Healthy Volunteers
• Immunomodulation

Identifiers and source

Literature Corpus work

51a766ea-7232-59c5-9721-f3020102fbff

DOI

10.1101/2021.08.06.455399