Article
The RNase E of Escherichia coli is a membrane-binding protein.
Molecular microbiology - 1 Nov 2008
Khemici Vanessa, Poljak Leonora, Luisi Ben F, Carpousis Agamemnon J
Abstract excerpt
RNase E is an essential endoribonuclease involved in RNA processing and mRNA degradation. The N-terminal half of the protein encompasses the catalytic domain; the C-terminal half is the scaffold for the assembly of the multienzyme RNA degradosome. Here we identify and characterize 'segment-A', an element in the beginning of the non-catalytic region of RNase E that is required for membrane binding. We demonstrate...
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