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Article

Systematic reconstruction of autism biology from massive genetic mutation profiles.

Science advances - 1 Apr 2018

Luo Weijun, Zhang Chaolin, Jiang Yong-Hui, Brouwer Cory R

Abstract excerpt

Autism spectrum disorder (ASD) affects 1% of world population and has become a pressing medical and social problem worldwide. As a paradigmatic complex genetic disease, ASD has been intensively studied and thousands of gene mutations have been reported. Because these mutations rarely recur, it is difficult to (i) pinpoint the fewer disease-causing versus majority random events and (ii) replicate or verify...

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Identifiers

PMID: 29651456
DOI: 10.1126/sciadv.1701799
PMCID: PMC5895441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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