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An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum

11 Jan 2021

Abstract excerpt

Establishing robust genome engineering methods in the malarial parasite, Plasmodium falciparum, has the potential to substantially improve the efficiency with which we gain understanding of this pathogen's biology to propel treatment and elimination efforts. Methods for manipulating gene expression and engineering the P. falciparum genome have been validated. However, a significant barrier to fully leveraging...

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PMID: 33431920
DOI: 10.1038/s41598-020-77644-4

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