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Optimization of CRISPR/Cas System for Improving Genome Editing Efficiency in Plasmodium falciparum

8 Jan 2021

Abstract excerpt

Studies of molecular mechanisms and related gene functions have long been restricted by limited genome editing technologies in malaria parasites. Recently, a simple and effective genome editing technology, the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system, has greatly facilitated these studies in many organisms, including malaria parasites. However, due to the...

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PMID: 33488567
DOI: 10.3389/fmicb.2020.625862

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