Article
Molecular profiling of the colon cancer in South-Eastern Romania: Results from the MERCUR study.
Medicine - 8 Jan 2021
Popescu Razvan Catalin, Tocia Cristina, Brînzan Costel, Cozaru Georgeta Camelia, Deacu Mariana, Dumitru Andrei, Leopa Nicoleta, Mitroi Anca Florentina, Nicolau Anca, Dumitru Eugen
Abstract excerpt
ABSTRACT: Colorectal cancer is a heterogeneous disease with multiple epigenetic alterations and different molecular features. The molecular classification is based on 2 major distinct pathways: microsatellite stable pathway and the microsatellite instability pathway. Molecular profiling of colorectal cancer provides important information regarding treatment and prognosis. Aim of the study was to assess the...
Topics
- Aged
- Colonic Neoplasms
- Female
- Humans
- Male
- Middle Aged
- Molecular Diagnostic Techniques
- Mutation
- Proto-Oncogene Proteins B-raf
- Romania
- Statistics, Nonparametric
