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Article

Predictors of poor response during asthma therapy differ with definition of outcome.

Pharmacogenomics - 1 Aug 2009

Rogers Angela J, Tantisira Kelan G, Fuhlbrigge Anne L, Litonjua Augusto A, Lasky-Su Jessica A, Szefler Stanley J, Strunk Robert C, Zeiger Robert S, Weiss Scott T

Abstract excerpt

AIMS: To evaluate phenotypic and genetic variables associated with a poor long-term response to inhaled corticosteroid therapy for asthma, based independently on lung function changes or asthma exacerbations. MATERIALS & METHODS: We tested 17 phenotypic variables and polymorphisms in FCER2 and CRHR1 in 311 children (aged 5-12 years) randomized to a 4-year course of inhaled corticosteroid during the Childhood...

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Topics

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Share to Administration, Inhalation
Share to Adrenal Cortex Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRF Receptor, Type 1

Share to Lectins, C-Type

Share to Receptors, Corticotropin-Releasing Hormone

Share to Receptors, IgE

Share to Recurrence

Share to Respiratory Function Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 19663668
DOI: 10.2217/pgs.09.86
PMCID: PMC2746392

Genes

CRHR1
FCER2
CAMP

Variants

RS242941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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