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Article

DNA methylation markers for cancer risk prediction of vulvar intraepithelial neoplasia

15 Jan 2021

Abstract excerpt

Abstract Current clinical and histological classifications are unable to determine the risk of vulvar squamous cell carcinoma (VSCC) in high‐grade vulvar intraepithelial neoplasia (VIN), making prognostic biomarkers highly needed. We studied host‐cell DNA methylation markers in high‐grade squamous intraepithelial lesion (HSIL) and differentiated VIN (dVIN) without VSCC, in HSIL and dVIN adjacent to VSCC and in...

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PMID: 33426639
DOI: 10.1002/ijc.33459

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