Article
Biological relevance of human papillomaviruses in vulvar cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2017
Halec Gordana, Alemany Laia, Quiros Beatriz, Clavero Omar, Höfler Daniela, Alejo Maria, Quint Wim, Pawlita Michael, Bosch Francesc X, de Sanjose Silvia
Abstract excerpt
The carcinogenic role of high-risk human papillomavirus (HR-HPV) types in the increasing subset of vulvar intraepithelial neoplasia and vulvar cancer in young women has been established. However, the actual number of vulvar cancer cases attributed to HPV is still imprecisely defined. In an attempt to provide a more precise definition of HPV-driven vulvar cancer, we performed HPV-type-specific E6*I mRNA analyses...
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