Article
Association between human leukocyte antigens (HLAs) and human neutrophil antigens (HNAs) and autoimmune neutropenia of infancy in Danish patients.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 May 2021
Nielsen Kaspar René, Bojsen Signe Rolskov, Masmas Tania Nicole, Fjordside Anne-Louise, Baech John, Haunstrup Thure Mors, Steffensen Rudi
Abstract excerpt
BACKGROUND: Autoimmune neutropenia of infancy (AIN) is a frequent cause of neutropenia in children. The disease is caused by antibodies against epitopes on the immunoglobulin G (IgG) Fc receptor type 3b (FcγIIIb). We investigated the possible association of human neutrophil antigens (HNA), human leukocyte antigen (HLA)-DR, and HLA-DQ alleles with AIN and the association of these genotypes with the presence of...
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