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Article

ABO, secretor, and Lewis carbohydrate histo-blood groups are associated with autoimmune neutropenia of early childhood in Danish patients.

Transfusion - 1 Aug 2022

Kløve-Mogensen Kirstine, Steffensen Rudi, Masmas Tania Nicole, Glenthøj Andreas, Haunstrup Thure Mors, Ratcliffe Paul, Höglund Petter, Hasle Henrik, Nielsen Kaspar René

Abstract excerpt

BACKGROUND: Autoimmune neutropenia of early childhood (AIN) is caused by autoantibodies directed against antigens on the neutrophil membrane. The ABO, secretor, and Lewis histo-blood group systems control the expression of carbohydrate antigens and have previously been linked to autoimmune diseases. We aimed to investigate the association between genotypes and the risk of AIN in Danish patients. STUDY DESIGN AND...

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Identifiers

PMID: 35792132
DOI: 10.1111/trf.17002
PMCID: PMC9544446

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