Article
Antibodies to human neutrophil antigen HNA-3b implicated in cases of neonatal alloimmune neutropenia.
Transfusion - 1 May 2018
Lopes Larissa Barbosa, Abbas Samira Ali, Moritz Elyse, Martins Juliana Oliveira, Chiba Akemi Kuroda, Langhi Dante Mário, Bordin José O
Abstract excerpt
BACKGROUND: Neonatal alloimmune neutropenia results from maternal alloimmunization to human neutrophil antigens. The alloantibodies involved in neonatal alloimmune neutropenia are against human neutrophil antigens HNA-1a, HNA-1b, HNA-1c, HNA-1d, HNA-2, HNA-3a, HNA-4a, HNA-4b, and HNA-5a; however, to date, antibodies specific to HNA-3b have not been reported. STUDY DESIGN AND METHODS: Blood samples from 10,000...
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