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Article

Serologic and molecular studies to identify neonatal alloimmune neutropenia in a cohort of 10,000 neonates.

British journal of haematology - 1 Feb 2021

Abbas Samira A, Lopes Larissa B, Moritz Elyse, Martins Juliana O, Chiba Akemi K, Kunioshi Alessandra M, Barbosa Elisama S, Langhi Junior Dante M, Dos Santos Amélia M N, Godinho Cárlei H, Bordin José O

Abstract excerpt

Neonatal alloimmune neutropenia (NAIN) is caused by maternal alloimmunisation to fetal human neutrophil antigens (HNAs). This study investigated maternal HNA/HLA alloantibodies involved with NAIN and identified the frequency of NAIN in Brazilian neonates. Neonatal neutropenia (neutrophil count < 1.5 × 109 /L) was investigated in samples from 10,000 unselected neonates, resulting in 88 neutropenic newborns (NBs)...

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Identifiers

PMID: 33529380
DOI: 10.1111/bjh.17295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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