Article
IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin.
The international journal of biochemistry & cell biology - 1 Jul 2009
Chakravorty Meenakshi, Datta De Dipanjana, Choudhury Abhijit, Roychoudhury Susanta
Abstract excerpt
It is important to dissect the effect of the alternative alleles of a functional SNP on the entire biochemical pathway for the complete understanding of the mechanism of the manifestation of complex diseases. IL1B-511C>T and -31C>T promoter polymorphisms have been suggested as potential susceptibility loci for Helicobacter pylori associated gastroduodenal diseases. We report that altered expression of IL1B due to...
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