Article
Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria.
The Journal of experimental medicine - 29 Jul 2013
Pinzon-Charry Alberto, Woodberry Tonia, Kienzle Vivian, McPhun Virginia, Minigo Gabriela, Lampah Daniel A, Kenangalem Enny, Engwerda Christian, López J Alejandro, Anstey Nicholas M, Good Michael F
Abstract excerpt
Malaria causes significant morbidity worldwide and a vaccine is urgently required. Plasmodium infection causes considerable immune dysregulation, and elicitation of vaccine immunity remains challenging. Given the central role of dendritic cells (DCs) in initiating immunity, understanding their biology during malaria will improve vaccination outcomes. Circulating DCs are particularly important, as they shape...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
