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Article

Diminished Expression Alleles for Analysis of Virulence Traits and Genetic Interactions in Candida albicans.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Woolford Carol A, Mitchell Aaron P

Abstract excerpt

Here we present a protocol of interest to those who want to look at the functional consequences of decreasing expression of essential genes constitutively as well as being able to study the regulatory pathways of that essential gene by also deleting one or two additional genes. This allows epistasis relationships to be determined.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33405027
DOI: 10.1007/978-1-0716-1182-1_1

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