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Article

Investigation of the Substrate-Binding Site of a Prostaglandin E Synthase in Bombyx mori.

The protein journal - 1 Feb 2021

Yamamoto Kohji, Hirowatari Aiko

Abstract excerpt

Prostaglandin E synthase (PGES) catalyzes the conversion of prostaglandin H2 to prostaglandin E2 in the presence of glutathione (GSH) in mammals. Amid the limited knowledge on prostaglandin and its related enzymes in insects, we recently identified PGES from the silkworm Bombyx mori (bmPGES) and determined its crystal structure complexed with GSH. In the current study, we investigated the substrate-binding site...

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Identifiers

PMID: 33403608
DOI: 10.1007/s10930-020-09956-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Investigation of the Substrate-Binding Site of a Prostaglandin E Synthase in Bombyx mori.PMID 33403608Read ↗

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